Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 3/20 | 0.37 |
| ▸ | INSR | P06213 | 2/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23153854 | 1.00 | EGFR (0.39) | EGFRZAP70IGF1RINSRALK | |
| SCHEMBL27162682 | 0.90 | ALK (0.46) | EGFRIGF1RINSRALKPTK2 | |
| SCHEMBL30741156 | 0.90 | ALK (0.46) | EGFRIGF1RINSRALKPTK2 | |
| SCHEMBL23154083 | 0.89 | ZAP70 (0.40) | EGFRZAP70IGF1RINSRALK | |
| SCHEMBL23153853 | 0.89 | EGFR (0.40) | EGFRIGF1RINSRALKPTK2 | |
| SCHEMBL23153875 | 0.86 | EGFR (0.42) | EGFRZAP70IGF1RINSRALK | |
| SCHEMBL29975976 | 0.86 | EGFR (0.42) | EGFRZAP70IGF1RINSRALK | |
| SCHEMBL23154196 | 0.85 | EGFR (0.38) | EGFRIGF1RINSRALKMEN1 | |
| SCHEMBL23153751 | 0.84 | EGFR (0.38) | EGFRZAP70IGF1RINSRALK | |
| SCHEMBL23153748 | 0.83 | EGFR (0.41) | EGFRIGF1RINSRALKPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425646-A | Phosphono derivative, composition thereof and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2024-01-19 | — | — | CN | disclosed |