Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 3/20 | 0.54 |
| ▸ | CFTR | P13569 | 5/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228476 | 0.79 | BAZ2B (0.61) | BAZ2BKDRCFTRLMNATRPV1 | |
| SCHEMBL21154472 | 0.79 | BAZ2B (0.61) | BAZ2BKDRCFTRLMNATRPV1 | |
| SCHEMBL7132310 | 0.78 | LMNA (0.68) | BAZ2BACHEKDRCFTRMAPKAPK2 | |
| SCHEMBL12868564 | 0.78 | LMNA (0.78) | BAZ2BACHEKDRCFTRLMNA | |
| SCHEMBL2189766 | 0.76 | BAZ2B (0.63) | BAZ2BACHELMNAPABPC1ATM | |
| SCHEMBL61901 | 0.76 | LMNA (0.60) | BAZ2BKDRLMNAPABPC1ATM | |
| SCHEMBL1000954 | 0.75 | TRPV1 (0.69) | KDRTRPV1HDAC1HDAC6 | |
| SCHEMBL12868460 | 0.75 | MAPT (0.62) | BAZ2BACHECFTRLMNAPABPC1 | |
| SCHEMBL11834686 | 0.75 | HTR1D (0.54) | BAZ2BACHEKDRADRA1DADRA1A | |
| SCHEMBL6245029 | 0.75 | MAPKAPK2 (0.64) | ACHEMAPKAPK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109928971-B | Aryl substituted aminotetrahydropyrans and uses thereof | 广东东阳光药业股份有限公司 | 2024-01-16 | — | — | CN | disclosed |