Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30743137 | 1.00 | HDAC2 (0.43) | HDAC2HDAC1HRH3GPR119GPR183 | |
| SCHEMBL31235897 | 0.86 | S1PR5 (0.41) | HDAC2HDAC1HRH3GPR119GPR183 | |
| SCHEMBL31235930 | 0.85 | GPR119 (0.40) | HDAC2HDAC1HRH3GPR119GPR183 | |
| SCHEMBL30743147 | 0.82 | NR1H2 (0.50) | HDAC2HDAC1HRH3GPR119GPR183 | |
| SCHEMBL30743131 | 0.80 | HDAC2 (0.41) | HDAC2HDAC1HRH3GPR119GPR183 | |
| SCHEMBL326175 | 0.79 | ESR2 (0.49) | HDAC1GPR119GPR183USP30S1PR5 | |
| SCHEMBL13261529 | 0.79 | GPR119 (0.43) | HDAC1GPR119GPR183PRSS1PRSS2 | |
| SCHEMBL38663673 | 0.78 | GPR119 (0.43) | HDAC1GPR119GPR183USP30S1PR5 | |
| SCHEMBL31236112 | 0.78 | STS (0.47) | HRH3GPR119GPR183PRSS1PRSS2 | |
| SCHEMBL2109867 | 0.77 | PRSS1 (0.58) | GPR119PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015346-A1 | CEREBLON LIGANDS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. d.b.a PROTEOVANT THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |