Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 5/20 | 0.41 |
| ▸ | TDO2 | P48775 | 5/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL326175 | 0.87 | ESR2 (0.49) | GPR119USP30IDO1TDO2HDAC1 | |
| SCHEMBL13261529 | 0.87 | GPR119 (0.43) | GPR119USP30IDO1TDO2HDAC1 | |
| SCHEMBL38663673 | 0.86 | GPR119 (0.43) | GPR119USP30IDO1TDO2HDAC1 | |
| SCHEMBL31235979 | 0.84 | IDO1 (0.46) | GPR119IDO1TDO2HDAC1HDAC8 | |
| SCHEMBL30743138 | 0.82 | HDAC2 (0.43) | NR1H2GPR119USP30HDAC1HDAC2 | |
| SCHEMBL30743137 | 0.82 | HDAC2 (0.43) | NR1H2GPR119USP30HDAC1HDAC2 | |
| SCHEMBL30743097 | 0.81 | NR1H2 (0.45) | NR1H2GPR119USP30HDAC1HDAC2 | |
| SCHEMBL31543806 | 0.81 | CRBN (0.42) | NR1H2GPR119USP30IDO1TDO2 | |
| SCHEMBL31329274 | 0.80 | NAMPT (0.40) | NR1H2GPR119USP30HDAC1HDAC2 | |
| SCHEMBL38661874 | 0.80 | USP30 (0.45) | GPR119USP30IDO1TDO2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025039999-A1 | FUSED HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-02-27 | — | — | WO | disclosed |
| WO-2024015346-A1 | CEREBLON LIGANDS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. d.b.a PROTEOVANT THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |