Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | RAB9A | P51151 | 7/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | PGR | P06401 | 1/20 | 0.63 |
| ▸ | AR | P10275 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | RAF1 | P04049 | 1/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | STAT1 | P42224 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295385 | 1.00 | TP53 (0.64) | TP53TSHRMAPTRAB9ANPC1 | |
| SCHEMBL21295431 | 0.91 | STK39 (0.58) | TP53TSHRMAPTRAB9ANPC1 | |
| SCHEMBL21305446 | 0.91 | STK39 (0.60) | TP53TSHRMAPTRAB9ANPC1 | |
| SCHEMBL30744028 | 0.91 | STK39 (0.60) | TP53TSHRMAPTRAB9ANPC1 | |
| SCHEMBL23051396 | 0.88 | KMT2A (0.58) | MAPTRAB9ANPC1SMN1; SMN2PGR | |
| SCHEMBL21295375 | 0.88 | TP53 (0.66) | TP53TSHRMAPTRAB9ANPC1 | |
| SCHEMBL30743987 | 0.88 | TP53 (0.66) | TP53TSHRMAPTRAB9ANPC1 | |
| SCHEMBL21295336 | 0.88 | MAPT (0.62) | TP53MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30743994 | 0.88 | MAPT (0.62) | TP53MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL21295549 | 0.86 | MAPT (0.61) | TP53TSHRMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819172-B | Triazine derivatives for the treatment of neurotrophin related diseases | 阿泽克制药公司 | 2024-02-06 | — | — | CN | disclosed |