Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.60 |
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | IDH1 | O75874 | 1/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | TEK | Q02763 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PNLIP | P16233 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21305446 | 1.00 | STK39 (0.60) | STK39DHODHPGRARIDH1 | |
| SCHEMBL21295431 | 0.97 | STK39 (0.58) | STK39DHODHPGRARIDH1 | |
| SCHEMBL21295331 | 0.94 | STK39 (0.56) | STK39DHODHPGRARIDH1 | |
| SCHEMBL21295557 | 0.93 | STK39 (0.57) | STK39DHODHPGRARIDH1 | |
| SCHEMBL30743998 | 0.93 | STK39 (0.57) | STK39DHODHPGRARIDH1 | |
| SCHEMBL21295412 | 0.92 | STK39 (0.62) | STK39DHODHPGRARNR1H4 | |
| SCHEMBL23051396 | 0.92 | KMT2A (0.58) | STK39DHODHPGRARIDH1 | |
| SCHEMBL30744002 | 0.92 | STK39 (0.54) | STK39DHODHPGRARIDH1 | |
| SCHEMBL21295337 | 0.92 | STK39 (0.54) | STK39DHODHPGRARIDH1 | |
| SCHEMBL21295385 | 0.91 | TP53 (0.64) | PGRARRAF1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819172-B | Triazine derivatives for the treatment of neurotrophin related diseases | 阿泽克制药公司 | 2024-02-06 | — | — | CN | disclosed |