Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21305484 | 1.00 | ALDH1A1 (0.45) | ALDH1A1CYP19A1PTGDR2HIF1AL3MBTL1 | |
| SCHEMBL16094987 | 0.88 | ALDH1A1 (0.43) | ALDH1A1CYP19A1PTGDR2HIF1AL3MBTL1 | |
| SCHEMBL16095891 | 0.83 | PTGDR2 (0.60) | ALDH1A1CYP19A1PTGDR2HIF1AKMT2A | |
| SCHEMBL16096315 | 0.83 | MAPT (0.49) | ALDH1A1KMT2AGAALMNAMAPT | |
| SCHEMBL3643810 | 0.81 | HTT (0.54) | ALDH1A1CYP19A1HIF1AL3MBTL1KMT2A | |
| SCHEMBL16096386 | 0.79 | ALDH1A1 (0.43) | ALDH1A1CYP19A1PTGDR2HIF1AL3MBTL1 | |
| SCHEMBL16096388 | 0.79 | PTGDR2 (0.41) | ALDH1A1CYP19A1PTGDR2HIF1AL3MBTL1 | |
| SCHEMBL30743999 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1CYP19A1PTGDR2HIF1AL3MBTL1 | |
| SCHEMBL21305402 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1CYP19A1PTGDR2HIF1AL3MBTL1 | |
| SCHEMBL2938530 | 0.78 | HTT (0.53) | ALDH1A1HIF1AL3MBTL1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819172-B | Triazine derivatives for the treatment of neurotrophin related diseases | 阿泽克制药公司 | 2024-02-06 | — | — | CN | disclosed |