Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 4/20 | 0.50 |
| ▸ | NTRK3 | Q16288 | 4/20 | 0.50 |
| ▸ | NTRK2 | Q16620 | 4/20 | 0.50 |
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295539 | 1.00 | NTRK1 (0.50) | NTRK1NTRK3NTRK2TTRMAOB | |
| SCHEMBL4061067 | 0.84 | ALDH1A1 (0.55) | GAAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL29736247 | 0.84 | ALDH1A1 (0.55) | GAAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL5548836 | 0.83 | MAPT (0.56) | NTRK1NTRK3NTRK2TTRMAOB | |
| SCHEMBL21340417 | 0.83 | L3MBTL1 (0.48) | NTRK1NTRK3NTRK2MAOBMAOA | |
| SCHEMBL14937721 | 0.81 | MAPT (0.50) | GAAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL15814937 | 0.81 | CYP19A1 (0.50) | MAOBMAOAGAAMAPTKMT2A | |
| SCHEMBL3811355 | 0.80 | TTR (0.58) | NTRK1NTRK2TTRMAOBMAOA | |
| SCHEMBL30222339 | 0.80 | TTR (0.58) | NTRK1NTRK2TTRMAOBMAOA | |
| SCHEMBL5649965 | 0.80 | KDM4E (0.56) | GAAKDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819172-B | Triazine derivatives for the treatment of neurotrophin related diseases | 阿泽克制药公司 | 2024-02-06 | — | — | CN | disclosed |