Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.56 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.56 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295383 | 1.00 | NTRK1 (0.56) | NTRK1NTRK3NTRK2MAOBMAOA | |
| SCHEMBL30744015 | 0.79 | NTRK1 (0.54) | NTRK1NTRK3NTRK2CYP1A2CYP3A4 | |
| SCHEMBL21295568 | 0.79 | NTRK1 (0.54) | NTRK1NTRK3NTRK2CYP1A2CYP3A4 | |
| SCHEMBL21295545 | 0.76 | NTRK1 (0.54) | NTRK1NTRK3NTRK2MEN1NPC1 | |
| SCHEMBL30140430 | 0.76 | HTR2C (0.37) | NTRK1NTRK3NTRK2CYP3A4MCHR1 | |
| SCHEMBL5548836 | 0.75 | MAPT (0.56) | NTRK1NTRK3NTRK2MAOBMAOA | |
| SCHEMBL21295371 | 0.74 | NTRK1 (0.52) | NTRK1NTRK3NTRK2KMT2AMCHR1 | |
| SCHEMBL30744035 | 0.74 | NTRK1 (0.52) | NTRK1NTRK3NTRK2KMT2AMCHR1 | |
| SCHEMBL19990170 | 0.74 | MAOA (0.56) | MAOBMAOANCOA1NCOA3CYP1A2 | |
| SCHEMBL5481920 | 0.74 | TDP1 (0.62) | NTRK1NTRK3NTRK2CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819172-B | Triazine derivatives for the treatment of neurotrophin related diseases | 阿泽克制药公司 | 2024-02-06 | — | — | CN | disclosed |