SCHEMBL5481920

SCHEMBL5481920

c1ccc(OCC2COC2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.62
ALDH1A1 P00352 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HIF1A Q16665 1/20 0.46
CARM1 Q86X55 1/20 0.44
PRMT6 Q96LA8 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
NTRK1 P04629 2/20 0.43
NTRK3 Q16288 2/20 0.43
NTRK2 Q16620 2/20 0.43
KCNA3 P22001 1/20 0.43
ADRA1A P35348 1/20 0.42
GRM2 Q14416 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
DRD2 P14416 1/20 0.41
DRD4 P21917 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16596108 0.92 TDP1 (0.58) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL24304923 0.81 APP (0.57) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL1990800 0.80 TDP1 (0.57) TDP1CARM1PRMT6DRD2DRD4
SCHEMBL13879696 0.80 APP (0.42) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL21051452 0.80 PARP15 (0.42) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL1278162 0.80 TDP1 (0.53) TDP1CARM1PRMT6DRD2DRD4
SCHEMBL17316594 0.80 TDP1 (0.40) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL15301046 0.80 TSHR (0.41) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL22290928 0.78 ALDH1A1 (0.50) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL4278181 0.78 TP53 (0.50) ALDH1A1TP53CYP3A4TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006118532-A1 HYBRID RADIATION CURABLE COMPOSITION AND USE THEREOF PERSTORP SPECIALTY CHEMICALS AB (SE) 2006-11-09 WO claimed
CN-109982829-A Thermoset composition and three-dimension object is formed by it 帝斯曼知识产权资产管理有限公司 2019-07-05 CN disclosed
CN-109890861-A Thermoset composition and three-dimension object is formed by it 帝斯曼知识产权资产管理有限公司 2019-06-14 CN disclosed
CN-104745104-B Photocurable adhesive agent composition, polarizer and its manufacturing method, optical component and liquid crystal display device 东亚合成株式会社 2019-06-07 CN disclosed
CN-107229184-A Coloring photosensitive combination, staining and curing thing therefrom, the manufacture method of display element and staining and curing thing 东京应化工业株式会社 2017-10-03 CN disclosed
CN-107229185-A The manufacture method of energy sensitivities composition, solidfied material and solidfied material 东京应化工业株式会社 2017-10-03 CN disclosed
US-8980829-B2 Aryl glycoside compound, preparation method and use thereof SHANGHAI YINGLI SCIENCE AND TECHNOLOGY CO., LTD (CN) 2015-03-17 US disclosed
US-7270883-B2 Film-forming composition, anti-reflection film, polarizing plate, image display apparatus, anti-pollution coating composition and anti-pollution article FUJIFILM CORPORATION (JP) 2007-09-18 US disclosed
US-20050053790-A1 Film-forming composition, anti-reflection film, polarizing plate, image display apparatus, anti-pollution coating composition and anti-pollution article FUJI PHOTO FILM CO., LTD. (JP) 2005-03-10 US disclosed