Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801066 | 1.00 | TDP1 (0.36) | TDP1L3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL21801122 | 0.91 | TDP1 (0.37) | TDP1L3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL21801082 | 0.90 | TDP1 (0.36) | TDP1L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL30629627 | 0.90 | TDP1 (0.36) | TDP1L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL21866050 | 0.88 | TDP1 (0.34) | TDP1L3MBTL1SMN1; SMN2TP53 | |
| SCHEMBL30744108 | 0.83 | SIGMAR1 (0.47) | KDM4ESIGMAR1CYP2D6 | |
| SCHEMBL21801221 | 0.83 | SIGMAR1 (0.47) | KDM4ESIGMAR1CYP2D6 | |
| SCHEMBL21801097 | 0.81 | MAOB (0.31) | ALDH1A1GAANPC1RAB9ACYP1A2 | |
| SCHEMBL21801074 | 0.81 | TDP1 (0.38) | TDP1L3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL30629637 | 0.81 | TDP1 (0.38) | TDP1L3MBTL1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |