Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801229 | 1.00 | MAOB (0.42) | MAOBHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL21801126 | 0.90 | MAOB (0.42) | MAOBHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL21801226 | 0.88 | MAOB (0.41) | MAOBHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL21801185 | 0.88 | MAOB (0.40) | MAOBHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL26680095 | 0.88 | MAOB (0.41) | MAOBHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL30744124 | 0.86 | HDAC3 (0.40) | MAOBHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL21801234 | 0.86 | HDAC3 (0.40) | MAOBHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL21865727 | 0.86 | ACHE (0.39) | MAOBHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL21801353 | 0.84 | MAOB (0.37) | MAOBHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL21801232 | 0.83 | MAOB (0.44) | MAOBHDAC3HDAC4HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |