Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 14/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.44 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501355 | 1.00 | ROCK2 (0.44) | ROCK2ROCK1MYLK4NAMPTHDAC7 | |
| SCHEMBL23501353 | 1.00 | ROCK2 (0.44) | ROCK2ROCK1MYLK4NAMPTHDAC7 | |
| SCHEMBL30744188 | 0.93 | ROCK2 (0.37) | ROCK2ROCK1MYLK4NAMPTHDAC7 | |
| SCHEMBL23501190 | 0.93 | ROCK2 (0.37) | ROCK2ROCK1MYLK4NAMPTHDAC7 | |
| SCHEMBL30744200 | 0.93 | ROCK2 (0.37) | ROCK2ROCK1MYLK4NAMPTHDAC7 | |
| SCHEMBL23501189 | 0.93 | ROCK2 (0.37) | ROCK2ROCK1MYLK4NAMPTHDAC7 | |
| SCHEMBL30002705 | 0.92 | ALDH1A1 (0.38) | ROCK2ROCK1MYLK4NAMPTGAA | |
| SCHEMBL23927688 | 0.91 | ROCK2 (0.39) | ROCK2ROCK1MYLK4NAMPTHDAC7 | |
| SCHEMBL23501278 | 0.91 | ROCK2 (0.44) | ROCK2ROCK1 | |
| SCHEMBL23501411 | 0.91 | ROCK2 (0.43) | ROCK2ROCK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979675-B | Small molecular sulfur-containing heterocyclic compound | 维眸生物科技（上海）有限公司 | 2023-12-19 | — | — | CN | disclosed |