Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 17/20 | 0.66 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.66 |
| ▸ | MYLK4 | Q86YV6 | 2/20 | 0.66 |
| ▸ | CDC7 | O00311 | 1/20 | 0.51 |
| ▸ | PLK4 | O00444 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.51 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.51 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | PAK4 | O96013 | 1/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | ROS1 | P08922 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501404 | 1.00 | ROCK2 (0.66) | ROCK2ROCK1MYLK4CDC7PLK4 | |
| SCHEMBL23501309 | 0.81 | ROCK2 (0.45) | ROCK2ROCK1MYLK4MAPK1CLK2 | |
| SCHEMBL30744203 | 0.81 | ROCK2 (0.45) | ROCK2ROCK1MYLK4MAPK1CLK2 | |
| Netarsudil-M1 SCHEMBL30692376 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| Netarsudil-M1 SCHEMBL21412824 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| Netarsudil-M1 SCHEMBL30607241 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| Netarsudil-M1 SCHEMBL9883166 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| Netarsudil-M1 SCHEMBL21430354 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| Netarsudil-M1 SCHEMBL30607238 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 | |
| Netarsudil-M1 SCHEMBL30607237 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1MYLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979675-B | Small molecular sulfur-containing heterocyclic compound | 维眸生物科技（上海）有限公司 | 2023-12-19 | — | — | CN | disclosed |