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Sugi Predict / Compounds / SCHEMBL30744278

SCHEMBL30744278

SCHEMBL30744278

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)CNC(=O)[C@H](CS)NC(C)=O)[C@@H](C)CC)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C(N)=O)C(C)C)[C@@H](C)CC

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ GRPR P30550 1/20 0.69
▸ NR3C1 P04150 3/20 0.68
▸ PTH1R Q03431 4/20 0.67
▸ GLP1R P43220 5/20 0.67
▸ CCKBR P32239 1/20 0.66
▸ RXFP1 Q9HBX9 1/20 0.66
▸ ECE1 P42892 1/20 0.65
▸ MUS81 Q96NY9 1/20 0.65
▸ IL23R Q5VWK5 3/20 0.64
▸ NPY2R P49146 2/20 0.64
▸ GHSR Q92847 2/20 0.64
▸ CXCR4 P61073 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30744286 0.97 NR3C1 (0.71) GRPRNR3C1PTH1RGLP1RCCKBR
SCHEMBL30148541 0.95 NR3C1 (0.74) NR3C1PTH1RGLP1RCCKBRRXFP1
SCHEMBL29412274 0.91 GLP1R (0.73) GRPRNR3C1PTH1RGLP1RCCKBR
SCHEMBL29395456 0.91 GLP1R (0.78) NR3C1PTH1RGLP1RCCKBRECE1
SCHEMBL29357856 0.91 GLP1R (0.77) NR3C1PTH1RGLP1RCCKBRECE1
SCHEMBL30411571 0.91 PTH1R (0.77) GRPRNR3C1PTH1RGLP1RCCKBR
SCHEMBL30683162 0.90 GLP1R (0.81) NR3C1PTH1RGLP1RCCKBRECE1
SCHEMBL31396476 0.90 PTH1R (0.74) NR3C1PTH1RGLP1RCCKBRECE1
SCHEMBL29540128 0.89 GLP1R (0.79) NR3C1PTH1RGLP1RCCKBRRXFP1
SCHEMBL29664425 0.89 GLP1R (0.72) NR3C1PTH1RGLP1RCCKBRECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-PP36692-P2 Clematis plant named ‘DP136’ EARLY MORNING LLC (US) 2025-05-20 — — US claimed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 — — US disclosed
US-PP36692-P2 Clematis plant named ‘DP136’ EARLY MORNING LLC (US) 2025-05-20 — — US disclosed
US-PP36692-P2 Clematis plant named ‘DP136’ EARLY MORNING LLC (US) 2025-05-20 — — US disclosed
US-11891457-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891457-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R GRPR 6/4885NR3C1 4084/4885PTH1R 89/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R GRPR 6/4885NR3C1 4084/4885PTH1R 89/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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