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SCHEMBL29412274

SCHEMBL29412274

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)C(C)C)[C@@H](C)O)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O)[C@@H](C)O)C(C)C

nearest known ligand 0.73

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 5/20 0.73
▸ PTH1R Q03431 9/20 0.73
▸ CCKBR P32239 1/20 0.71
▸ GRPR P30550 1/20 0.71
▸ ECE1 P42892 1/20 0.69
▸ MUS81 Q96NY9 1/20 0.69
▸ RXFP1 Q9HBX9 1/20 0.68
▸ NR3C1 P04150 3/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30411571 0.94 PTH1R (0.77) GLP1RPTH1RCCKBRGRPRECE1
SCHEMBL30744286 0.94 NR3C1 (0.71) GLP1RPTH1RCCKBRGRPRECE1
SCHEMBL29395456 0.93 GLP1R (0.78) GLP1RPTH1RCCKBRECE1MUS81
SCHEMBL29357856 0.93 GLP1R (0.77) GLP1RPTH1RCCKBRECE1MUS81
SCHEMBL29540128 0.92 GLP1R (0.79) GLP1RPTH1RCCKBRECE1MUS81
SCHEMBL30683162 0.92 GLP1R (0.81) GLP1RPTH1RCCKBRECE1MUS81
SCHEMBL30148541 0.92 NR3C1 (0.74) GLP1RPTH1RCCKBRECE1MUS81
SCHEMBL31396476 0.92 PTH1R (0.74) GLP1RPTH1RCCKBRECE1MUS81
SCHEMBL30744278 0.91 GRPR (0.69) GLP1RPTH1RCCKBRGRPRECE1
SCHEMBL30008333 0.91 PTH1R (0.66) GLP1RPTH1RCCKBRGRPRECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3129044-B1 PEPTIDOGLYCAN HYDROLASE FOR USE IN THE TREATMENT OF CHRONIC BACTERIAL INFECTIONS LYSANDO AG (LI) 2022-09-07 — — EP claimed
WO-2025107024-A1 TRANSGENIC INSECTS AND PREPARATIONS THEREOF MACQUARIE UNIVERSITY (AU) 2025-05-30 — — WO disclosed
WO-2024113002-A1 TRANSGENIC INSECTS AND PREPARATIONS THEREOF MACQUARIE UNIVERSITY (AU) 2024-06-06 — — WO disclosed
US-11958890-B2 Antimicrobial proteins LYSANDO AG (LI) 2024-04-16 — — US disclosed
US-20240099281-A1 TRANSGENIC ANIMALS AND PREPARATIONS THEREOF FOR BIOREMEDIATION MACQUARIE UNIVERSITY (AU) 2024-03-28 — — US disclosed
US-11866750-B2 Endolysin variant SASINAPAS CO., LTD. (TH) 2024-01-09 — — US disclosed
CN-109072211-B Antibacterial agent against salmonella 莱桑多股份公司 2023-10-27 — — CN disclosed
EP-3409685-B1 INSOLUBLE FUSION PROTEIN COMPRISING ANTIMICROBIAL PEPTIDE AND METHOD FOR PRODUCING ANTIMICROBIAL PEPTIDE USING SAME UNIV KONKUK IND COOP CORP (KR) 2023-04-05 — — EP disclosed
EP-3129044-B1 PEPTIDOGLYCAN HYDROLASE FOR USE IN THE TREATMENT OF CHRONIC BACTERIAL INFECTIONS LYSANDO AG (LI) 2022-09-07 — — EP disclosed
US-11427812-B2 Antimicrobial agents against Staphylococcus aureus LYSANDO AG (LI) 2022-08-30 — — US disclosed
WO-2022126177-A1 TRANSGENIC ANIMALS AND PREPARATIONS THEREOF FOR BIOREMDIATION MACQUARIE UNIVERSITY (AU) 2022-06-23 — — WO disclosed
EP-3978605-A1 ANTIMICROBIAL AGENTS AGAINST SALMONELLA BACTERIA Lysando AG (LI) 2022-04-06 — — EP disclosed
EP-3541406-B1 NEW ANTIMICROBIAL AGENTS AGAINST STAPHYLOCOCCUS AUREUS LYSANDO AG (LI) 2022-03-16 — — EP disclosed
US-20220064623-A1 ENDOLYSIN VARIANT SASINAPAS CO., LTD. (TH) 2022-03-03 — — US disclosed
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