Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 2/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21492162 | 1.00 | NR1H3 (0.49) | NR1H3NR1H2UTS2RLMNAKMT2A | |
| SCHEMBL4854039 | 0.84 | NR1H3 (0.62) | NR1H3NR1H2UTS2RLMNAKMT2A | |
| SCHEMBL21503296 | 0.79 | UTS2R (0.49) | NR1H3NR1H2UTS2RLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL21492876 | 0.76 | LMNA (0.51) | LMNAKMT2ARXFP1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30744459 | 0.76 | LMNA (0.51) | LMNAKMT2ARXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10926180 | 0.76 | CASP3 (0.56) | UTS2RKMT2ARXFP1TP53MAPT | |
| SCHEMBL29195353 | 0.75 | NR1H3 (0.55) | NR1H3NR1H2UTS2RLMNAKMT2A | |
| SCHEMBL8777049 | 0.73 | LMNA (0.72) | NR1H3NR1H2LMNAALDH1A1MAPT | |
| SCHEMBL12177051 | 0.72 | KMT2A (0.71) | NR1H3NR1H2UTS2RLMNAKMT2A | |
| SCHEMBL18669081 | 0.72 | TDP1 (0.70) | UTS2RLMNAKMT2ARXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-B | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2024-03-12 | — | — | CN | disclosed |