Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21492952 | 1.00 | TKT (0.34) | TKTPDE4BP2RX7ADRB1PSEN1 | |
| SCHEMBL21491806 | 0.85 | TKT (0.32) | TKTPDE4BP2RX7ADRB1 | |
| SCHEMBL26697497 | 0.84 | TKT (0.33) | TKT | |
| SCHEMBL21503672 | 0.83 | GABRA1 (0.33) | TKTADRB1 | |
| SCHEMBL2866080 | 0.75 | TKT (0.40) | TKTPDE4BP2RX7 | |
| SCHEMBL3872590 | 0.73 | PDE4B (0.37) | TKTPDE4BP2RX7ADRB1 | |
| SCHEMBL28489701 | 0.73 | TKT (0.35) | TKTPDE4BP2RX7ADRB1 | |
| SCHEMBL1474657 | 0.72 | TRPV1 (0.42) | TKTPDE4BP2RX7ADRB1 | |
| SCHEMBL4492952 | 0.72 | TKT (0.36) | TKTPDE4BP2RX7ADRB1PSEN1 | |
| SCHEMBL21625533 | 0.72 | AR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-B | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2024-03-12 | — | — | CN | disclosed |