Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744698 | 0.84 | TKT (0.34) | TKT | |
| SCHEMBL21492952 | 0.84 | TKT (0.34) | TKT | |
| SCHEMBL21491806 | 0.83 | TKT (0.32) | TKT | |
| SCHEMBL21503672 | 0.80 | GABRA1 (0.33) | TKT | |
| SCHEMBL21503616 | 0.75 | KDM4E (0.38) | TKTTRPV1 | |
| SCHEMBL21625533 | 0.70 | AR (0.37) | — | |
| SCHEMBL28533492 | 0.69 | SCD5 (0.40) | — | |
| SCHEMBL30744336 | 0.69 | SCD5 (0.35) | — | |
| SCHEMBL21492743 | 0.69 | SCD5 (0.35) | — | |
| SCHEMBL24908479 | 0.69 | PDE4B (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784669-B1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMA (US) | 2023-10-25 | — | — | EP | disclosed |