Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 2/20 | 0.54 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2329950 | 1.00 | CD44 (0.54) | CD44PRCPPNMTMAOBTRPA1 | |
| SCHEMBL5087669 | 0.88 | PNMT (0.56) | CD44PRCPPNMTMAOB | |
| SCHEMBL29801575 | 0.88 | PNMT (0.56) | CD44PRCPPNMTMAOB | |
| Hydrochloric Acid SCHEMBL17822916 | 0.86 | PNMT (0.54) | CD44PRCPPNMTMAOB | |
| SCHEMBL17559798 | 0.86 | PRCP (0.51) | CD44PRCPPNMTMAOBTSHR | |
| SCHEMBL27901033 | 0.85 | CD44 (0.57) | CD44PNMTMAOBTRPA1ALOX15 | |
| SCHEMBL30314450 | 0.85 | CD44 (0.57) | CD44PNMTMAOBTRPA1ALOX15 | |
| SCHEMBL1817879 | 0.84 | ALDH1A1 (0.43) | CD44PRCPPNMTTRPA1ALDH1A1 | |
| SCHEMBL29662964 | 0.84 | ALDH1A1 (0.43) | CD44PRCPPNMTTRPA1ALDH1A1 | |
| SCHEMBL2355554 | 0.81 | CD44 (0.49) | CD44PNMTMAOBTRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |