Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | KDM4A | O75164 | 2/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | KDM6A | O15550 | 1/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
| ▸ | KDM4B | O94953 | 1/20 | 0.50 |
| ▸ | KDM5C | P41229 | 1/20 | 0.50 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.50 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.50 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744842 | 0.88 | KDM4E (0.52) | KDM4EKDM4AEGLN1L3MBTL1KDM6B | |
| SCHEMBL23233760 | 0.78 | KDM4E (0.67) | KDM4EKDM4AKDM4CPDE4DPDE4A | |
| SCHEMBL20554452 | 0.77 | EGFR (0.46) | PDE4DTBK1 | |
| SCHEMBL20944544 | 0.77 | KDM4E (0.49) | KDM4EKDM4AEGLN1L3MBTL1KDM6B | |
| SCHEMBL30744993 | 0.77 | KDM4E (0.49) | KDM4EKDM4AEGLN1L3MBTL1KDM6B | |
| SCHEMBL30744755 | 0.76 | KDM4E (0.54) | KDM4EKDM4AEGLN1L3MBTL1KDM6B | |
| SCHEMBL20963907 | 0.76 | KDM4E (0.64) | KDM4EPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL4022814 | 0.74 | PDE4A (0.64) | KDM4EKDM4AEGLN1L3MBTL1KDM6B | |
| SCHEMBL4700871 | 0.74 | KDM4E (0.57) | KDM4EKDM4AEGLN1L3MBTL1KDM6B | |
| Hydrochloric Acid SCHEMBL6984422 | 0.73 | PDE4A (0.62) | KDM4EKDM4AEGLN1L3MBTL1KDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |