Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | AGER | Q15109 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 2/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30595866 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL5241823 | 0.89 | KDM4E (0.55) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| Hydrochloric Acid SCHEMBL3242526 | 0.87 | KDM4E (0.53) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL286833 | 0.85 | KDM4E (0.55) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL11919498 | 0.84 | NFE2L2 (0.39) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| Hydrochloric Acid SCHEMBL3058112 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL28244005 | 0.78 | BRD4 (0.55) | KDM4EALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL11532432 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL9696695 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL14208205 | 0.74 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |