Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20944292 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1HPGDNPSR1STAT3 | |
| SCHEMBL16008196 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1HPGDNPSR1STAT3 | |
| SCHEMBL31547755 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1HPGDNPSR1STAT3 | |
| SCHEMBL27922983 | 0.75 | PLA2G2A (0.55) | KDM4EALDH1A1HPGDNPSR1STAT3 | |
| SCHEMBL30301713 | 0.75 | CNR2 (0.52) | KDM4ENPSR1STAT3HIF1AMEN1 | |
| SCHEMBL7631322 | 0.75 | CNR2 (0.52) | KDM4ENPSR1STAT3HIF1AMEN1 | |
| SCHEMBL7016481 | 0.73 | LMNA (0.51) | KDM4EALDH1A1NPSR1STAT3HIF1A | |
| SCHEMBL29966579 | 0.73 | LCK (0.50) | KDM4EALDH1A1HPGDNPSR1MEN1 | |
| SCHEMBL15369528 | 0.73 | LCK (0.50) | KDM4EALDH1A1HPGDNPSR1MEN1 | |
| SCHEMBL29865696 | 0.73 | LCK (0.50) | KDM4EALDH1A1HPGDNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |