Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA7 | P43166 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16011716 | 1.00 | CYP3A4 (0.49) | CYP3A4ACHENPSR1CA12CA1 | |
| SCHEMBL28413248 | 0.83 | CA12 (0.47) | CYP3A4ACHENPSR1CA12CA1 | |
| SCHEMBL30748264 | 0.83 | CA12 (0.47) | CYP3A4ACHENPSR1CA12CA1 | |
| SCHEMBL8272321 | 0.83 | ATM (0.50) | CYP3A4ACHENPSR1ATML3MBTL1 | |
| SCHEMBL31347580 | 0.83 | ATM (0.50) | CYP3A4ACHENPSR1ATML3MBTL1 | |
| SCHEMBL719767 | 0.81 | ATM (0.53) | NPSR1CA12CA1CA2CA7 | |
| SCHEMBL15900223 | 0.80 | NPSR1 (0.42) | NPSR1CA12CA1CA2CA7 | |
| SCHEMBL2592299 | 0.80 | AGBL2 (0.47) | CYP3A4ACHENPSR1ATML3MBTL1 | |
| SCHEMBL22477293 | 0.80 | CYP3A4 (0.49) | CYP3A4NPSR1CA1CA2HPGD | |
| SCHEMBL10314919 | 0.80 | NPSR1 (0.42) | CYP3A4ACHENPSR1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |