SCHEMBL2592299

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29738141	0.84	NPSR1 (0.43)	AGBL2NPSR1KDM4EALDH1A1SMN1; SMN2
	SCHEMBL644695	0.84	NPSR1 (0.43)	AGBL2NPSR1KDM4EALDH1A1SMN1; SMN2
	SCHEMBL14260604	0.82	OPRK1 (0.47)	AGBL2NPSR1KDM4EALDH1A1SMN1; SMN2
	SCHEMBL31347580	0.81	ATM (0.50)	NPSR1KDM4EALDH1A1SMN1; SMN2HSD17B10
	SCHEMBL8272321	0.81	ATM (0.50)	NPSR1KDM4EALDH1A1SMN1; SMN2HSD17B10
	SCHEMBL26928475	0.81	AGBL2 (0.50)	AGBL2KDM4ESMN1; SMN2SSTR4BACE1
	SCHEMBL16505782	0.81	NPSR1 (0.41)	AGBL2NPSR1KDM4EALDH1A1SMN1; SMN2
	SCHEMBL16632434	0.81	NPSR1 (0.41)	AGBL2NPSR1KDM4EALDH1A1SMN1; SMN2
	SCHEMBL319381	0.81	NPSR1 (0.41)	AGBL2NPSR1KDM4EALDH1A1SMN1; SMN2
	SCHEMBL15991274	0.81	KDM4E (0.42)	NPSR1KDM4EALDH1A1SMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.