Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1854891 | 1.00 | LMNA (0.56) | LMNAKDM4EKMT2AMEN1NPSR1 | |
| SCHEMBL7466621 | 0.91 | KMT2A (0.51) | LMNAKDM4EKMT2AMEN1NPSR1 | |
| SCHEMBL4112022 | 0.85 | RAB9A (0.61) | LMNAKMT2AMEN1NPSR1MAPT | |
| SCHEMBL27672005 | 0.84 | SMN1; SMN2 (0.55) | LMNAKDM4EKMT2AMEN1MAPT | |
| SCHEMBL6174966 | 0.84 | SMN1; SMN2 (0.59) | LMNAKDM4EKMT2AMEN1RAB9A | |
| SCHEMBL4035515 | 0.84 | MAPT (0.56) | LMNAKDM4EKMT2AMEN1MAPT | |
| SCHEMBL3855637 | 0.84 | CA1 (0.48) | LMNAKDM4EMAPTTDP1GAA | |
| SCHEMBL24803508 | 0.83 | LMNA (0.53) | LMNAKDM4EKMT2AMEN1NPSR1 | |
| SCHEMBL6283849 | 0.83 | SMN1; SMN2 (0.54) | LMNAKDM4EKMT2AMEN1MAPT | |
| SCHEMBL24803573 | 0.83 | KMT2A (0.51) | LMNAKDM4EKMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |