Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745057 | 0.81 | LMNA (0.54) | ALDH1A1LMNAHPGDUSP2TSHR | |
| SCHEMBL30745039 | 0.77 | NPSR1 (0.44) | ALDH1A1LMNATSHRMAPTATM | |
| SCHEMBL30744991 | 0.75 | LMNA (0.48) | ALDH1A1LMNAHPGDMAPTTDP1 | |
| SCHEMBL30688568 | 0.75 | MAPT (0.55) | ALDH1A1LMNAHPGDUSP2TSHR | |
| SCHEMBL522937 | 0.74 | TSHR (0.50) | ALDH1A1LMNAHPGDUSP2TSHR | |
| SCHEMBL20944034 | 0.73 | EDNRA (0.52) | LMNAHPGDMCL1EDNRAGABRP | |
| SCHEMBL31636486 | 0.73 | ALDH1A1 (0.51) | ALDH1A1LMNAHPGDUSP2TSHR | |
| SCHEMBL31636619 | 0.73 | USP2 (0.51) | ALDH1A1LMNAHPGDUSP2TSHR | |
| SCHEMBL30745076 | 0.73 | MAPT (0.57) | ALDH1A1LMNAHPGDUSP2TSHR | |
| SCHEMBL31636613 | 0.73 | USP2 (0.48) | ALDH1A1LMNAHPGDUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |