Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SDHB | P21912 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20944312 | 1.00 | MAPT (0.39) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL3099034 | 0.85 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL3098843 | 0.81 | SYK (0.39) | LOXL2ALPLALPISYKRBP4 | |
| SCHEMBL20944049 | 0.80 | MAPT (0.39) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL21199850 | 0.78 | SMN1; SMN2 (0.43) | MAPTKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL21200024 | 0.77 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL2342015 | 0.77 | NQO2 (0.46) | MAPTKDM4EALDH1A1HPGDSDHB | |
| SCHEMBL2340704 | 0.77 | MAPT (0.52) | MAPTKDM4EALDH1A1HPGDSDHB | |
| SCHEMBL20944381 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL21199812 | 0.77 | NOTUM (0.54) | MAPTKDM4EALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |