Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27145832 | 0.85 | ACACB (0.47) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4316682 | 0.84 | CYP1A2 (0.56) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23716298 | 0.79 | CYP1A2 (0.45) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29938041 | 0.78 | MAPT (0.48) | CYP1A2CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL1110936 | 0.78 | HPGD (0.53) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2325264 | 0.78 | MAPT (0.48) | CYP1A2CYP2D6CYP2C9CYP2C19LMNA | |
| SCHEMBL1813466 | 0.77 | MAPT (0.47) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13343583 | 0.77 | ALDH1A1 (0.55) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30744983 | 0.77 | MAPT (0.47) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5846153 | 0.76 | GAA (0.51) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |