Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20943981 | 1.00 | NOTUM (0.47) | NOTUMMAPTCFTRMRGPRX4KDM4E | |
| SCHEMBL21044587 | 0.84 | NOTUM (0.53) | NOTUMMAPTCFTRKDM4EALDH1A1 | |
| SCHEMBL21201020 | 0.82 | MRGPRX4 (0.38) | NOTUMMAPTCFTRMRGPRX4KDM4E | |
| SCHEMBL16303300 | 0.78 | NOTUM (0.47) | NOTUMMAPTCFTRKDM4EALDH1A1 | |
| SCHEMBL19787929 | 0.78 | MAPT (0.43) | NOTUMMAPTMRGPRX4KDM4EALDH1A1 | |
| SCHEMBL16505957 | 0.77 | NOTUM (0.46) | NOTUMMAPTCFTRKDM4EALDH1A1 | |
| SCHEMBL12455673 | 0.77 | BACE1 (0.41) | MAPTMRGPRX4KDM4EALDH1A1KMT2A | |
| SCHEMBL29910288 | 0.77 | CFTR (0.53) | NOTUMMAPTCFTRKDM4EALDH1A1 | |
| SCHEMBL2088462 | 0.77 | CFTR (0.53) | NOTUMMAPTCFTRKDM4EALDH1A1 | |
| SCHEMBL30261881 | 0.77 | NOTUM (0.46) | NOTUMMAPTCFTRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |