Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16303300 | 0.90 | NOTUM (0.47) | NOTUMCFTRMAPTGPR35KDM4E | |
| SCHEMBL21044459 | 0.90 | NOTUM (0.47) | NOTUMCFTRMAPTKDM4EALDH1A1 | |
| SCHEMBL30261881 | 0.88 | NOTUM (0.46) | NOTUMCFTRMAPTGPR35KDM4E | |
| SCHEMBL2088462 | 0.88 | CFTR (0.53) | NOTUMCFTRMAPTGPR35KDM4E | |
| SCHEMBL16505957 | 0.88 | NOTUM (0.46) | NOTUMCFTRMAPTGPR35KDM4E | |
| SCHEMBL29910288 | 0.88 | CFTR (0.53) | NOTUMCFTRMAPTGPR35KDM4E | |
| SCHEMBL23326908 | 0.84 | ADORA3 (0.49) | NOTUMCFTRMAPTGPR35KDM4E | |
| SCHEMBL20943981 | 0.84 | NOTUM (0.47) | NOTUMCFTRMAPTGPR35KDM4E | |
| SCHEMBL29910346 | 0.84 | ADORA3 (0.49) | NOTUMCFTRMAPTGPR35KDM4E | |
| SCHEMBL30745008 | 0.84 | NOTUM (0.47) | NOTUMCFTRMAPTGPR35KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191451-B1 | 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME | OKINAWA INST SCIENCE & TECH SCHOOL CORP (JP) | 2019-06-05 | — | — | EP | claimed |