Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 7/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745141 | 0.98 | CA12 (0.42) | CA12CA1CA14CA7CTSK | |
| SCHEMBL18343872 | 0.95 | CA12 (0.44) | CA12CA1CA14CA7CTSK | |
| SCHEMBL28038096 | 0.88 | CA1 (0.46) | CA12CA1CA14CA7CTSK | |
| SCHEMBL28301926 | 0.83 | CA12 (0.46) | CA12CA1CA14CA7CTSK | |
| SCHEMBL11255950 | 0.78 | CA2 (0.38) | CA1CA2FAAHCES2CES1 | |
| SCHEMBL28572752 | 0.76 | KMT2A (0.40) | CA12CA1CA14CA7CTSK | |
| SCHEMBL3458070 | 0.75 | TDP1 (0.42) | CA12CA1CA14CA7CA2 | |
| SCHEMBL28430499 | 0.73 | CA12 (0.41) | CA12CA1CA14CA7CTSK | |
| SCHEMBL1859283 | 0.73 | EPHX1 (0.43) | CA12CA1CA14CA7CTSK | |
| SCHEMBL27959208 | 0.73 | CA2 (0.37) | CA12CA1CA14CA7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510470-A | Pyridazinone compounds and application thereof | 暨南大学 | 2024-02-06 | — | — | CN | disclosed |