SCHEMBL11255950

SCHEMBL11255950

CCCCCS(=O)(=O)ONC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.38
FAAH O00519 5/20 0.38
PLA2G2C Q5R387 1/20 0.37
CES2 O00748 6/20 0.37
CES1 P23141 5/20 0.37
CA1 P00915 1/20 0.35
CA9 Q16790 1/20 0.35
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28177673 0.86 KDM4E (0.35) PLA2G2C
SCHEMBL27959208 0.79 CA2 (0.37) CA2FAAHCA1CA9
SCHEMBL9264991 0.79 ZDHHC20 (0.46) CA2FAAHCES2CES1EPHX2
SCHEMBL6335517 0.78 CA2 (0.40) CA2FAAHCA1CA9
SCHEMBL27796743 0.78 ZDHHC20 (0.49) CA2FAAHCES2CES1EPHX2
SCHEMBL28108566 0.78 ZDHHC20 (0.49) CA2FAAHCES2CES1EPHX2
SCHEMBL28555015 0.78 ZDHHC20 (0.45) CA2FAAHCES2CES1EPHX2
SCHEMBL28035331 0.78 ZDHHC20 (0.49) CA2FAAHCES2CES1EPHX2
SCHEMBL30745146 0.78 CA12 (0.43) CA2FAAHCES2CES1CA1
SCHEMBL28135575 0.78 ZDHHC20 (0.49) CA2FAAHCES2CES1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0095177-A1 Process for the preparation of N-acetylamino-aryl-sulphonic acids HOECHST AKTIENGESELLSCHAFT (DE) 1983-11-30 EP disclosed