Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 11/20 | 0.53 |
| ▸ | FGFR2 | P21802 | 10/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.52 |
| ▸ | FGFR4 | P22455 | 7/20 | 0.52 |
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | MET | P08581 | 5/20 | 0.48 |
| ▸ | MST1R | Q04912 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | YES1 | P07947 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14793376 | 0.83 | PDGFRB (0.62) | FGFR3FGFR2FGFR1FGFR4KDR | |
| SCHEMBL14915862 | 0.81 | MET (0.58) | FGFR3FGFR2FGFR1FGFR4KDR | |
| SCHEMBL29151085 | 0.78 | FGFR2 (0.56) | FGFR3FGFR2FGFR1FGFR4KDR | |
| SCHEMBL3256828 | 0.78 | FGFR3 (0.56) | FGFR3FGFR2FGFR1FGFR4KDR | |
| SCHEMBL20391249 | 0.77 | MET (0.48) | FGFR3FGFR2FGFR1FGFR4KDR | |
| SCHEMBL19649969 | 0.76 | MET (0.55) | FGFR3FGFR2FGFR1FGFR4KDR | |
| SCHEMBL29870004 | 0.76 | FGFR2 (0.53) | FGFR3FGFR2FGFR1FGFR4KDR | |
| SCHEMBL28687573 | 0.76 | MET (0.58) | FGFR3FGFR2FGFR1FGFR4MET | |
| SCHEMBL29870068 | 0.76 | MET (0.58) | FGFR3FGFR2FGFR1FGFR4MET | |
| SCHEMBL29870028 | 0.76 | MET (0.60) | FGFR3FGFR2FGFR1FGFR4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510470-A | Pyridazinone compounds and application thereof | 暨南大学 | 2024-02-06 | — | — | CN | disclosed |