Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | ADH1B | P00325 | 1/20 | 0.53 |
| ▸ | ADH1C | P00326 | 1/20 | 0.53 |
| ▸ | ADH1A | P07327 | 1/20 | 0.53 |
| ▸ | ADH7 | P40394 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3305893 | 1.00 | CHRM2 (0.59) | CHRM2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL3305905 | 0.94 | ALDH1A1 (0.57) | CHRM2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL24061767 | 0.94 | CHRM2 (0.54) | CHRM2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL24061766 | 0.89 | ALDH1A1 (0.68) | CHRM2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL1134127 | 0.83 | CHRM2 (0.74) | CHRM2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL5548185 | 0.83 | SMN1; SMN2 (0.57) | CHRM2ALDH1A1SMN1; SMN2ADH1BADH1C | |
| SCHEMBL2473241 | 0.83 | CHRM2 (0.66) | CHRM2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL22912213 | 0.83 | ALDH1A1 (0.56) | CHRM2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL5537789 | 0.82 | ADH1B (0.49) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4881807 | 0.82 | TSHR (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113956249-B | Brain-targeted AChE inhibitor prodrug, and preparation method and application thereof | 中国药科大学 | 2024-02-02 | — | — | CN | claimed |
| CN-113956249-B | Brain-targeted AChE inhibitor prodrug, and preparation method and application thereof | 中国药科大学 | 2024-02-02 | — | — | CN | disclosed |