Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 3/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30054601 | 0.78 | GPR119 (0.42) | GPR119ARCCNCCDK8USP30 | |
| SCHEMBL24792051 | 0.78 | GPR119 (0.42) | GPR119ARCCNCCDK8USP30 | |
| SCHEMBL30740837 | 0.77 | GPR119 (0.44) | GPR119ARGPR6IRAK4 | |
| SCHEMBL30745359 | 0.76 | MRGPRX4 (0.39) | GPR119ARUSP30 | |
| SCHEMBL29826921 | 0.76 | GPR119 (0.43) | GPR119GPR6 | |
| SCHEMBL29826175 | 0.76 | GPR119 (0.52) | GPR119GPR6IRAK4 | |
| SCHEMBL30745407 | 0.76 | USP30 (0.38) | GPR119ARUSP30 | |
| SCHEMBL27478827 | 0.75 | GPR119 (0.42) | GPR119GPR6 | |
| SCHEMBL29826479 | 0.75 | GPR119 (0.42) | GPR119GPR6 | |
| SCHEMBL30745387 | 0.74 | MRGPRX4 (0.37) | GPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |