Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745407 | 0.86 | USP30 (0.38) | MRGPRX4CYP3A4CYP3A5GPR119USP30 | |
| SCHEMBL30745387 | 0.85 | MRGPRX4 (0.37) | MRGPRX4CYP3A4CYP3A5GPR119USP30 | |
| SCHEMBL30745390 | 0.85 | MRGPRX4 (0.37) | MRGPRX4CYP3A4CYP3A5GPR119USP30 | |
| SCHEMBL30745352 | 0.81 | MRGPRX4 (0.48) | MRGPRX4GPR119ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL30745395 | 0.79 | MEN1 (0.35) | GPR119USP30 | |
| SCHEMBL24791791 | 0.77 | GPR119 (0.47) | MRGPRX4CYP3A4CYP3A5GPR119USP30 | |
| SCHEMBL31413096 | 0.76 | USP30 (0.46) | CYP3A4CYP3A5GPR119USP30ALDH1A1 | |
| SCHEMBL30745358 | 0.76 | GPR119 (0.42) | GPR119USP30AR | |
| SCHEMBL29580612 | 0.74 | MEN1 (0.39) | GPR119USP30ALDH1A1 | |
| SCHEMBL31598413 | 0.71 | TRPV3 (0.36) | CYP3A4CYP3A5GPR119USP30CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |