Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 16/20 | 0.53 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24791693 | 1.00 | GLP1R (0.53) | GLP1RACSS2 | |
| SCHEMBL24791618 | 0.94 | GLP1R (0.59) | GLP1R | |
| SCHEMBL30745365 | 0.83 | GLP1R (0.51) | GLP1R | |
| SCHEMBL24792581 | 0.83 | GLP1R (0.51) | GLP1R | |
| SCHEMBL30745398 | 0.80 | GLP1R (0.58) | GLP1R | |
| SCHEMBL29157120 | 0.80 | GLP1R (0.58) | GLP1R | |
| SCHEMBL29825972 | 0.79 | GLP1R (0.51) | GLP1RACSS2 | |
| SCHEMBL30740849 | 0.79 | GLP1R (0.51) | GLP1RACSS2 | |
| SCHEMBL29826815 | 0.77 | ACSS2 (0.46) | GLP1RACSS2 | |
| SCHEMBL30740795 | 0.77 | ACSS2 (0.46) | GLP1RACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |