Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745369 | 0.84 | PDE4B (0.50) | ALDH1A1MAPTLMNATSHRHTT | |
| SCHEMBL24793022 | 0.84 | PDE4B (0.50) | ALDH1A1MAPTLMNATSHRHTT | |
| SCHEMBL30745421 | 0.84 | PDE4B (0.50) | ALDH1A1MAPTLMNATSHRHTT | |
| SCHEMBL24793021 | 0.84 | PDE4B (0.50) | ALDH1A1MAPTLMNATSHRHTT | |
| SCHEMBL24792598 | 0.84 | PDE4B (0.50) | ALDH1A1MAPTLMNATSHRHTT | |
| SCHEMBL30745366 | 0.84 | MRGPRX4 (0.49) | ALDH1A1MAPTLMNATSHRHTT | |
| SCHEMBL30745393 | 0.83 | MRGPRX4 (0.47) | ALDH1A1MAPTLMNATSHRHTT | |
| SCHEMBL30745404 | 0.82 | MRGPRX4 (0.49) | ALDH1A1MAPTLMNATSHRHTT | |
| SCHEMBL30745379 | 0.81 | MRGPRX4 (0.47) | ALDH1A1MAPTLMNATSHRHTT | |
| SCHEMBL8223030 | 0.80 | RIPK1 (0.51) | ALDH1A1MAPTLMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |