Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27168908 | 0.85 | MRGPRX4 (0.48) | MRGPRX4MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL24793341 | 0.85 | MRGPRX4 (0.48) | MRGPRX4MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30745367 | 0.84 | ALDH1A1 (0.49) | MRGPRX4TSHRLMNAMAPTNPSR1 | |
| SCHEMBL30745352 | 0.83 | MRGPRX4 (0.48) | MRGPRX4TSHRLMNAMAPTNPSR1 | |
| SCHEMBL30740730 | 0.83 | MRGPRX4 (0.46) | MRGPRX4TSHRLMNAMAPTNPSR1 | |
| SCHEMBL29826265 | 0.78 | CACNB4 (0.49) | MRGPRX4 | |
| SCHEMBL30745343 | 0.76 | TSHR (0.44) | MRGPRX4TSHRLMNAMAPTNPSR1 | |
| SCHEMBL28961568 | 0.76 | ALDH1A1 (0.59) | TSHRLMNAMAPTNPSR1MEN1 | |
| SCHEMBL31306996 | 0.76 | TSHR (0.44) | TSHRLMNAMAPTNPSR1MEN1 | |
| SCHEMBL30740732 | 0.75 | MRGPRX4 (0.45) | MRGPRX4TSHRLMNAALDH1A1EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |