Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | GRB2 | P62993 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620374 | 1.00 | CAMK2A (0.51) | CAMK2AALDH1A1LMNAGLACYP2C9 | |
| SCHEMBL1644783 | 0.84 | EGFR (0.49) | CAMK2AALDH1A1LMNAGLACYP2C9 | |
| SCHEMBL10479066 | 0.82 | PTGDR2 (0.42) | ALDH1A1LMNAGLACYP2C9HPGD | |
| SCHEMBL29710650 | 0.82 | PTGDR2 (0.42) | ALDH1A1LMNAGLACYP2C9HPGD | |
| SCHEMBL156238 | 0.81 | TYR (0.60) | CAMK2AALDH1A1LMNAGLACYP2C9 | |
| SCHEMBL29419312 | 0.81 | TYR (0.60) | CAMK2AALDH1A1LMNAGLACYP2C9 | |
| SCHEMBL27743914 | 0.81 | POLB (0.50) | NPSR1POLB | |
| SCHEMBL4047837 | 0.78 | KEAP1 (0.50) | CAMK2ACYP2C9AKR1B1 | |
| SCHEMBL909444 | 0.78 | PKM (0.53) | TSHRAKR1B1 | |
| SCHEMBL2729900 | 0.78 | HPGD (0.42) | CAMK2AALDH1A1LMNACYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |