Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 2/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.39 |
| ▸ | GRM5 | P41594 | 7/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27007919 | 1.00 | SOS1 (0.42) | SOS1WDR5PDK4GRM1GRM5 | |
| SCHEMBL27007900 | 0.96 | SOS1 (0.40) | SOS1WDR5PDK4GRM1GRM5 | |
| SCHEMBL27007833 | 0.90 | SOS1 (0.50) | SOS1WDR5PDK4GRM1GRM5 | |
| SCHEMBL27025908 | 0.87 | NAMPT (0.47) | SOS1PDK4GRM1GRM5NAMPT | |
| SCHEMBL27007927 | 0.87 | SOS1 (0.48) | SOS1WDR5PDK4GRM1GRM5 | |
| SCHEMBL27007723 | 0.83 | SOS1 (0.35) | SOS1WDR5HSD11B1 | |
| SCHEMBL27007572 | 0.82 | HSD11B1 (0.39) | HSD11B1 | |
| SCHEMBL27025905 | 0.81 | GRM1 (0.41) | SOS1WDR5PDK4GRM1GRM5 | |
| SCHEMBL27025890 | 0.79 | GRM1 (0.51) | PDK4GRM1GRM5NAMPT | |
| SCHEMBL34465791 | 0.79 | NR1H2 (0.47) | SOS1WDR5PDK4GRM1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018121-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMCIAL DIVERSITY CENTER, INC. (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018121-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | ERG28, CYP51A1, MANBA | SOS1 4010/4885WDR5 2039/4885PDK4 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.