Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27007875 | 0.98 | SOS1 (0.40) | SOS1NAMPTTRPV1MMP2MMP3 | |
| SCHEMBL27025892 | 0.90 | NAMPT (0.37) | SOS1NAMPTMMP2MMP3PRMT5 | |
| SCHEMBL27007946 | 0.90 | SOS1 (0.38) | SOS1NAMPTTRPV1MMP2MMP3 | |
| SCHEMBL27007723 | 0.90 | SOS1 (0.35) | SOS1TRPV1MMP2MMP3WDR5 | |
| SCHEMBL27025807 | 0.89 | NAMPT (0.43) | SOS1NAMPTGRM5GRM1PDK4 | |
| SCHEMBL27025875 | 0.89 | CDK9 (0.37) | SOS1NAMPTPRMT5WDR77GRM5 | |
| SCHEMBL27007901 | 0.89 | NAMPT (0.38) | SOS1NAMPTMMP2MMP3PRMT5 | |
| SCHEMBL27025883 | 0.89 | NAMPT (0.38) | SOS1NAMPTMMP2MMP3PRMT5 | |
| SCHEMBL30745991 | 0.88 | SOS1 (0.37) | SOS1NAMPTMMP2MMP3PRMT5 | |
| SCHEMBL27007644 | 0.88 | SOS1 (0.37) | SOS1NAMPTMMP2MMP3PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018121-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMCIAL DIVERSITY CENTER, INC. (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018121-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | ERG28, CYP51A1, MANBA | SOS1 4010/4885NAMPT 639/4885TRPV1 4745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.