Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26984846 | 1.00 | NUDT1 (0.43) | NUDT1KMT2AEGFRNPC1HPGD | |
| SCHEMBL31613417 | 0.78 | NUDT1 (0.43) | NUDT1KMT2AEGFRSMN1; SMN2TRPM5 | |
| SCHEMBL26985143 | 0.78 | NUDT1 (0.43) | NUDT1KMT2AEGFRSMN1; SMN2TRPM5 | |
| SCHEMBL4156639 | 0.77 | SCN9A (0.54) | KMT2AEGFRMEN1LMNAMAPT | |
| SCHEMBL29707607 | 0.77 | SCN9A (0.54) | KMT2AEGFRMEN1LMNAMAPT | |
| SCHEMBL16487061 | 0.76 | L3MBTL1 (0.60) | KMT2ASMN1; SMN2MEN1LMNAMAPT | |
| SCHEMBL30746670 | 0.76 | NUDT1 (0.46) | NUDT1KMT2AEGFRNPC1HPGD | |
| SCHEMBL26984979 | 0.76 | NUDT1 (0.46) | NUDT1KMT2AEGFRNPC1HPGD | |
| SCHEMBL30746411 | 0.75 | NUDT1 (0.42) | NUDT1KMT2AEGFRNPC1HPGD | |
| SCHEMBL16861944 | 0.75 | GRM4 (0.39) | KMT2AEGFRMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120129678-A | Mitogen-activated protein kinase (MEK) inhibitors | 耐斯泰德医疗公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |