Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | RBM39 | Q14498 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26984933 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1TDP1RECQL | |
| SCHEMBL26985182 | 0.85 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1TDP1RECQL | |
| SCHEMBL30746472 | 0.85 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1TDP1RECQL | |
| SCHEMBL34463286 | 0.75 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1TDP1RECQL | |
| SCHEMBL26984980 | 0.74 | GABRG2 (0.40) | KMT2A | |
| SCHEMBL29904955 | 0.74 | GAA (0.78) | ALDH1A1KMT2AMEN1TDP1RECQL | |
| SCHEMBL31613391 | 0.74 | GABRG2 (0.40) | KMT2A | |
| SCHEMBL28710064 | 0.73 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1TDP1RECQL | |
| SCHEMBL32690983 | 0.72 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1TDP1RECQL | |
| SCHEMBL8581980 | 0.72 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1TDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120129678-A | Mitogen-activated protein kinase (MEK) inhibitors | 耐斯泰德医疗公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |