Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 12/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26984854 | 1.00 | NCEH1 (0.51) | NCEH1PKMRAB9ANPC1TSHR | |
| SCHEMBL9939386 | 0.81 | LMNA (0.38) | PKMRAB9ANPC1TSHRLMNA | |
| SCHEMBL30746702 | 0.71 | NCEH1 (0.37) | NCEH1PKMRAB9ANPC1TSHR | |
| SCHEMBL26985713 | 0.71 | NCEH1 (0.37) | NCEH1PKMRAB9ANPC1TSHR | |
| SCHEMBL3256483 | 0.70 | L3MBTL1 (0.35) | RAB9ANPSR1 | |
| SCHEMBL31184958 | 0.67 | ATM (0.44) | PKMTSHRLMNA | |
| SCHEMBL9939057 | 0.67 | ATM (0.44) | PKMTSHRLMNA | |
| SCHEMBL17644390 | 0.67 | ITGB1 (0.39) | NCEH1PKMRAB9ANPC1TSHR | |
| SCHEMBL8375858 | 0.67 | KDM4E (0.46) | NCEH1PKMRAB9ANPC1TSHR | |
| SCHEMBL152386 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120129678-A | Mitogen-activated protein kinase (MEK) inhibitors | 耐斯泰德医疗公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |