Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | MST1R | Q04912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26985192 | 1.00 | SLC6A2 (0.34) | SLC6A2SLC6A4CYP17A1HTR1AMET | |
| SCHEMBL30746596 | 0.90 | SLC6A2 (0.39) | SLC6A2SLC6A4MET | |
| SCHEMBL26984914 | 0.90 | SLC6A2 (0.39) | SLC6A2SLC6A4MET | |
| SCHEMBL30746386 | 0.81 | RAF1 (0.38) | SLC6A2SLC6A4MET | |
| SCHEMBL26984864 | 0.81 | RAF1 (0.38) | SLC6A2SLC6A4MET | |
| SCHEMBL26985152 | 0.80 | MET (0.36) | SLC6A2SLC6A4HTR1AMETKDR | |
| SCHEMBL30746374 | 0.80 | MET (0.36) | SLC6A2SLC6A4HTR1AMETKDR | |
| SCHEMBL26984893 | 0.75 | MET (0.34) | MET | |
| SCHEMBL30746636 | 0.75 | MET (0.34) | MET | |
| SCHEMBL30746394 | 0.74 | AOC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120129678-A | Mitogen-activated protein kinase (MEK) inhibitors | 耐斯泰德医疗公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |