⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26985255 | 1.00 | — | — | |
| SCHEMBL26984875 | 0.88 | KDM4E (0.35) | — | |
| SCHEMBL30746604 | 0.88 | DHFR (0.34) | — | |
| SCHEMBL30746454 | 0.88 | KDM4E (0.35) | — | |
| SCHEMBL26985336 | 0.88 | DHFR (0.34) | — | |
| SCHEMBL26984964 | 0.86 | — | — | |
| SCHEMBL30746577 | 0.86 | — | — | |
| SCHEMBL26984868 | 0.86 | NUDT1 (0.42) | — | |
| SCHEMBL30746672 | 0.86 | MAPK1 (0.35) | — | |
| SCHEMBL26984845 | 0.86 | MAPK1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120129678-A | Mitogen-activated protein kinase (MEK) inhibitors | 耐斯泰德医疗公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |