SCHEMBL30747788

SCHEMBL30747788

CP(C)(=O)c1nc(N)c2nc[nH]c2n1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 1/20 0.33
PNP P00491 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27249496 1.00 GDA (0.33) GDAPNP
SCHEMBL30747789 0.84 TLR7 (0.33) GDA
SCHEMBL27249600 0.84 TLR7 (0.33) GDA
SCHEMBL15412191 0.83 GDA (0.33) GDAPNP
SCHEMBL27249683 0.83
SCHEMBL30747762 0.83
SCHEMBL30747729 0.82 TLR7 (0.36)
SCHEMBL27249660 0.82 TLR7 (0.36)
SCHEMBL5025525 0.75 ADK (0.33)
2,6-Diaminopurine SCHEMBL1074475 0.75 GDA (0.41) GDAPNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4554678-A1 PHOSPHORYLPURINONE COMPOUNDS FOR THE TREATMENT OF CANCER F. Hoffmann-La Roche AG (CH) 2025-05-21 EP disclosed
WO-2024013205-A9 PHOSPHORYLPURINONE COMPOUNDS FOR THE TREATMENT OF CANCER F. HOFFMANN-LA ROCHE AG (CH) 2025-04-10 WO disclosed
WO-2024013205-A1 PHOSPHORYLPURINONE COMPOUNDS FOR THE TREATMENT OF CANCER F. HOFFMANN-LA ROCHE AG (CH) 2024-01-18 WO disclosed