Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140064 | 1.00 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL18315290 | 0.86 | HSD17B10 (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL10330185 | 0.86 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL3088832 | 0.86 | DRD4 (0.54) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL946142 | 0.83 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL18945536 | 0.83 | HSD17B10 (0.49) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL829177 | 0.82 | AR (0.65) | KDM4EALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL30406641 | 0.82 | AR (0.59) | KDM4EALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL3611154 | 0.81 | AR (0.73) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL9424119 | 0.81 | LMNA (0.62) | KDM4EALDH1A1HPGDHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538072-B | Aminopyrimidine EGFR inhibitors | 齐鲁制药有限公司 | 2024-02-06 | — | — | CN | disclosed |